A nucleic acid-based orthopoxvirus vaccine targeting the vaccinia virus L1, A27, B5 and A33 proteins protects rabbits against lethal rabbitpox virus aerosol challenge

In the age of COVID, nucleic acid vaccines have garnered much attention, at least in part, because of the simplicity of construction, production, and flexibility to adjust and adapt to an evolving outbreak. Orthopoxviruses remain a threat on multiple fronts, especially as emerging zoonosis. In response, we developed a DNA vaccine, termed 4pox, that protected … Read more

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

The potential use of smallpox as a biological weapon has led to the production and stockpiling of smallpox vaccine and the immunization of some healthcare workers. Another public health goal is the licensing of a safer vaccine that could benefit the millions of people advised not to take the current one because they or their … Read more

METAFECTENE® PRO , 1ml

HIGHLIGHT: Suitable for transfection of DNA, mRNA, siRNA, and miRNA, as well as for cotransfection of DNA and RNA Suitable for stable and transient transfection Suitable for adherent and suspended cells. Minimized toxic effects Optimized transfection rates Free of serum inhibition Complete library of user reports Wide range of references in specialized literature METAFECTENE® PRO … Read more

EpiMag HT Magnetic Separator

Product description The EpiMag HT (96-Well) Magnetic Separator is a magnetic holder (magnetic rack) that allows the precipitation of paramagnetic beads from liquid samples from various 96-well flat-bottomed or U-microplates (we recommend our EpiMag 96-well microplates for compatibility). Engineered from reused Greiner microplates, it ensures a high degree of microplate compatibility while remaining extremely economical … Read more

MethylFlash Methylated DNA Quantification

Product description The MethylFlash ™ Methylated DNA Quantitation Kit (Colorimetric) is a comprehensive set of buffers and reagents optimized to quantify overall DNA methylation colorimetrically by specifically measuring 5-methylcytosine (5-mC) levels in an ELISA-like microplate format. Compared to LUMA or LINE-1, Alu, and LTR-based assays, MethylFlash ™ technology directly quantifies true global DNA methylation. This … Read more

MethylFlash Global DNA Methylation 5-MC

Product description The MethylFlash ™ Global DNA Methylation (5-mC) ELISA Easy Kit is a complete set of buffers and reagents optimized to colorimetrically quantify the global methylation status of DNA by specifically measuring 5-methylcytosine (5-mC) levels in a simplified format. , “one-step” reaction similar to ELISA. This makes it possible to directly measure global DNA … Read more

Fitamp blood and cultured DNA KIT

Product description The FitAmp ™ Blood and Cultured Cell DNA Extraction Kit is a comprehensive set of essential components designed for the rapid isolation of pure genomic DNA. The researcher can quickly and efficiently isolate DNA from blood leukocytes and cultured mammalian cells. The entire procedure can be completed in 20 minutes. Fast: the entire … Read more

5-HT (Serotonin) 2C Receptor Antibody

The ImmunoStar 5-HT2C receptor antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat choroid plexus and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/500 – 1/1000 in PBS – Bn/Av-HRP technique. Intensification methods such as nickel will approximately double the dilution factor as … Read more

5-HT (Serotonin) 2A Receptor Antibody

The antibody is provided as 100 uL of affinity-purified serum in PBS (0.02 M sodium phosphate with 0.15 M sodium chloride, pH 7.5) with 1% BSA (bovine serum albumin), and 0.02% sodium azide.  Reacts with mouse, rat, and rabbit species. The images above labeled “ImmunoStar Rabbit 5-HT 2A receptor antibody” are the results of staining … Read more

5-HT (Serotonin) 1A Receptor Antibody

The histochemical antibody for the 5-HT1A receptor is generated in a rabbit against a synthetic peptide sequence corresponding to amino acids 294-312 of the rat 5-HT1A receptor. The antiserum is provided as 100 µl of affinity-purified serum containing 1% BSA. Controls: The ImmunoStar 5-HT1A receptor antiserum was quality control tested using standard immunohistochemical methods. The … Read more